Walk for the Juvenile Diabetes Research Foundation

On October 28 I will be walking in the Walk to Cure Diabetes event benefiting the Mid-Jersey Chapter of the Juvenile Diabetes Research Foundation.

My personal fund raising goal is $1000. I would appreciate any support that you could give me for this very worthwhile cause.

Since there are more than 18 million Americans affected by diabetes, I believe that my work with JDRF is important and well worth the effort. I am particularly proud of the fact that JDRF has provided more funding for diabetes research than any other non-governmental agency in the world.

Please visit my Walk Web page if you would like to donate online or see how close I am to reaching my personal goal:

Thank you for considering this request for your support. If you have any questions about the Walk to Cure Diabetes, or the work of the Juvenile Diabetes Research Foundation, please do not hesitate to call me.

Information on my walk:

Mid-Jersey Chapter
28 Kennedy Boulevard, Suite 180
East Brunswick, NJ 08816
(732)296-7171
midjersey@jdrf.org
http://www.jdrf.org/NJ/Mid-Jersey

Walk Info
Cook College, Rutgers the State University of New Jersey
10/28/2007
Start Time: 10:00 AM
Registration: 9 AM

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Under control

I am feeling pretty good about myself. I have made a concerted effort to keep my BG under control and I am having success. I have been using the excellent tools at SugarStats.com to track my BG and insulin dosage. You can see the graph below.blood glucose graph

Not bad. My goal is to get the average to about 100. My insulin dosage has gone up though. I was average about 12 units a day of Novolog and now I am just over 18 per day. Using both of these graphs I get to see a direct correlation between insulin dosage and blood glucose.
insulin dosage graph

Guinea Pig

The results of my recent blood tests indicate I have an HbA1c of 7.5. What!!!! No way. This does not make sense to me. I test 5-6 times a day, before and after meals. According to my meter (FreeStyle Flash) my 15 days average is 104. That should put the HbA1c between 5 and 6. Something strange is happening here.

I just finished reading “Think like a pancreas” and I remember reading about the Dawn Phenomenon. While sleeping the body releases certain hormones which can have the effect of raising blood sugar. One can go to bed with a reading of 95 and wake up with a reading of 108. So I performed a test. I went to bed at 10 PM and woke up during the night (2AM and 4 AM) to take blood glucose readings. The numbers are as follow:

Time meter reading
10 PM 95 mg/dL
2 AM 95 mg/dL
4 AM 94 mg/dL
6:30 AM 108 mg/dL

The last set of numbers I took just after waking up. My numbers appear to be higher in the morning than they were when I went to bed. For my last blood test, I recall my bedtime numbers ( I need to start keeping a log ) before going to bed were just over 100. The lab tests show that my urine glucose was 128 mg/dL and my blood glucose was 111 mg/dL the morning I took the test ( about 7:30 AM). Does this mean I suffer from the Dawn Phenomenon? This would likely explain that rather high HbA1c number.

So how do I deal with this? Not sure. I can skip my bedtime snack. I did that last night and my BG was 108 mg/dL so that was not much help. I plan to increase my basal dosage by 1 unit and repeat last nights tests. I guess some experimentation ( on myself !! ) is in order. Now I’m scared!!

Latent Autoimmune Diabetes in Adults (LADA)

My wife recently brought home a book on Type 1 diabetes from the local library. I was skimming through when I came upon the acronym LADA or Google and the WikiPedia.

Here’s and excerpt from article which you can find here.

Latent Autoimmune Diabetes in Adults (LADA) is a genetically-linked, hereditary autoimmune disorder that results in the body mistaking the pancreas as foreign and responds by attacking and destroying the insulin-producing beta islet cells of the pancreas. Simply stated, autoimmune disorders, including LADA, are an “allergy to self.”

In its early stages LADA typically presents as type 2 diabetes and is often misdiagnosed as such. However, LADA more closely resembles juvenile (type 1) diabetes and shares common physiological characteristics of type 1 for metabolic dysfunction, genetics, and autoimmune features, but LADA does not affect children and is classified distinctly as being separate from juvenile diabetes.

Treatment

There is no cure for Type 1 diabetes.

There is some evidence that it is triggered by a virus that changes the pancreatic cells in a way that prompts the immune system to attack them. …… Treatment includes a diet limited in carbohydrates and saturated fat, exercise to burn glucose, and regular insulin injections, sometimes administered via a portable insulin pump.

diabetes mellitus

From Answers.com

A severe, chronic form of diabetes caused by insufficient production of insulin and resulting in abnormal metabolism of carbohydrates, fats, and proteins. The disease, which typically appears in childhood or adolescence, is characterized by increased sugar levels in the blood and urine, excessive thirst, frequent urination, acidosis, and wasting. Also called insulin-dependent diabetes, type 1 diabetes.

From an article at http://www.nih.gov/news/pr/jun2006/niddk-09.htm
Type 1 diabetes is caused by a combination of genetic and environmental factors. About 18 regions of the genome have been linked to type 1 diabetes risk. The most well studied region is IDDM1, which contains the human leukocyte antigen (HLA) genes that encode immune response proteins. Specific variations in these genes predispose a person to the disease, but having them does not guarantee that someone will develop the disease. One or more external co-factors, such as a viral infection or component of the diet, appear to trigger immune cells’ misguided attack on beta cells in genetically susceptible people. Researchers are working to identify all the genes and environmental triggers that contribute to the risk of developing type 1 diabetes, and they have already learned a great deal about assessing an individual’s level of risk.


I am taking insulin 4 times a day. Three units of Novolog 10 minutes before each meal, three times daily. 8 units of lantus with a snack before bedtime.

From lantus.com

Prescription Lantus® is for adults with type 2 diabetes or adults and children (6 years and older) with type 1 diabetes who require long-acting insulin for the control of high blood sugar.

NovoLog® is a rapid-acting insulin analog.